The digital cultural and creative industry has become an important engine for high-quality economic development in the Guangdong-Hong Kong-Macao Greater Bay Area. This paper constructs an evaluation index system covering five dimensions: industrial scale, digital infrastructure, innovation capacity, market consumption, and open linkage. Using grey relational analysis, it quantitatively measures the core influencing factors of the digital cultural and creative industry clusters in the three regions from 2020 to 2024. The empirical results show that market consumption is the primary factor driving cluster integration, the correlation of open linkage factors exceeds expectations, and the correlation of workforce factors is the lowest, reflecting the substitution effect of digital technology on labor. Based on this, this paper proposes a path design for integration and innovation from four dimensions: technological empowerment, spatial synergy, institutional breakthrough, and market co-cultivation.