Volume 10,Issue 4
Influence Mechanism of Wendan Decoction on Cognitive Function of Schizophrenia: From Neurotransmitter to Signal Pathway
Schizophrenia is a serious mental disorder, often accompanied by significant cognitive impairment, which seriously affects the quality of life and social function of patients. As a traditional Chinese medicine prescription composed of Pinellia ternata, Pericarpium Citri Reticulatae and Poria cocos, recent studies have shown that Wendan Decoction has potential benefits in improving the cognitive performance of patients with schizophrenia. This paper reviews the mechanism of Wendan Decoction in improving the cognitive ability of patients with schizophrenia, focusing on its effects on neurotransmitter regulation, signal pathway regulation and neuroprotection. By integrating the existing experimental research and clinical observation data, this paper analyzed the intervention effect of Wendan Decoction active ingredients on the core pathophysiological process of schizophrenia, revealed its possible target and molecular mechanism, and provided new theoretical basis and ideas for the treatment of cognitive dysfunction in schizophrenia with traditional Chinese medicine.
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