Volume 6,Issue 4
Evaluation of the Application Value of Routine Blood Tests in the Diagnosis of Iron Deficiency Anemia
Objective: To explore the application significance of routine blood testing in the diagnosis of iron deficiency anemia (IDA), analyze the diagnostic effects of different single indicators and combinations of indicators, and provide optimization strategies for early and accurate clinical diagnosis. Methods: 86 patients with suspected iron deficiency anemia admitted to our hospital from August 2024 to August 2025 were selected. Routine blood tests were performed on all patients. Serum ferritin detection combined with bone marrow iron staining was used as the benchmark standard to compare and analyze each individual indicator and the sensitivity, specificity and accuracy of 5 indicator combinations (MCV + MCH, MCV + MCH + MCHC, MCV + MCH + RDW, RBC + Hb + MCV, Hb + MCV + MCH + MCHC). Results: There were 62 IDA patients and 24 non-IDA patients diagnosed according to the baseline standards. Among single indicators, MCV and MCH have the best diagnostic effect; among indicator combinations, the Hb + MCV + MCH + MCHC quadruple combination has the highest diagnostic efficiency (sensitivity 95.16%, specificity 91.67%, accuracy 94.19%), followed by the MCV + MCH + MCHC triple combination. Both groups are significantly better than other combinations and single indicators (P < 0.05). Conclusion: Among routine blood tests, the quadruple combination of Hb + MCV + MCH + MCHC is the most effective in diagnosing IDA, and the triple combination of MCV + MCH + MCHC is more cost-effective. It can be combined with actual clinical selection to provide reliable support for early screening and auxiliary diagnosis of IDA.
[1] Zhou X, Zhai S, 2023, Analysis of the Application Value of Routine Blood Testing in the Differential Diagnosis of Thalassemia and Iron Deficiency Anemia. Clinical Research, 31(1): 126–129.
[2] Wang J, 2021, Analysis of the Value of Routine Blood Testing in Distinguishing Iron Deficiency Anemia and Thalassemia. Contemporary Medicine, 27(3): 154–155.
[3] Xie C, 2019, The Application Value of Routine Blood Tests in the Diagnosis of Thalassemia. Chinese Contemporary Medicine, 26(26): 97–100.
[4] Xu W, 2019, Diagnostic Value of Routine Blood Testing for Iron Deficiency Anemia in Infants and Young Children. World Latest Medical Information Abstracts, 19(67): 212 + 215.
[5] Zhang J, 2019, The Application Value of Routine Blood Testing in the Diagnosis of Iron Deficiency Anemia. World Latest Medical Information Abstracts, 19(54): 148 + 150.
[6] Liu K, 2019, Analysis of the Application Value of Routine Blood Tests in the Diagnosis and Identification of Common Anemia. Journal of Clinical Rational Drug Use, 12(8): 130–131.
[7] Lin L, Lin P, 2019, Observation on the Application Effect of Routine Blood Tests in the Diagnosis of Thalassemia and Iron Deficiency Anemia. Chinese and Foreign Medical Research, 17(2): 62–64.
[8] Zhang C, Huang L, 2018, Change Characteristics of Routine Blood Tests in Patients with Thalassemia and Iron Deficiency Anemia. Journal of Clinical Rational Drug Use, 11(22): 131–133.