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Volume 10,Issue 4

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26 December 2025

Overview of Veterinary Drug Residues in Animal-Derived Foods and Detection Technologies

Kai Cao*
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1 College of Animal Science and Technology Guangxi Vocational Agricultural University, Nanning 530009, Guangxi, China
JMDS 2025 , 10(4), 206–214; https://doi.org/10.18063/JMDS.v10i4.1209
© 2025 by the Author. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution -Noncommercial 4.0 International License (CC BY-NC 4.0) ( https://creativecommons.org/licenses/by-nc/4.0/ )
Abstract

Veterinary drug residues pose a global challenge to the safety of animal-derived foods, presenting significant potential threats and hazards to human health. Based on this, this paper systematically reviews optimization strategies for enhancing analytical sensitivity and efficiency in three veterinary drug residue pretreatment techniques: liquid-liquid extraction, solid-phase extraction, and QuEChERS. It elaborates on detection technologies including microbial suppression, immunoassays, high-performance liquid chromatography, gas chromatography-mass spectrometry, liquid chromatography-tandem mass spectrometry (LC-MS/MS), surface-enhanced raman spectroscopy (SERS), electrochemical sensor technology, nucleic acid aptamer sensors, AI-assisted data analysis, and biomimetic recognition materials. This aims to strengthen veterinary drug residue regulation, standardize the healthy development of animal husbandry, increase investment in detection technology R&D, achieve international alignment of detection techniques, and provide technical support for ensuring the safety of food derived from animals.

Keywords
Animal-derived food
Veterinary drug residues
Pretreatment methods
Detection techniques
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