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Volume 11,Issue 1

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16 March 2026

Study on the Correlation between Standardized Treatment and Perinatal Outcomes in Pregnancy Complicated by Hypothyroidism

Chunmei Jiang*
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1 The Sixth People’s Hospital of Haimen District, Nantong 226152, Jiangsu, China
JMDS 2026 , 11(1), 23–28; https://doi.org/10.18063/JMDS.v11i1.1348
© 2026 by the Author. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution -Noncommercial 4.0 International License (CC BY-NC 4.0) ( https://creativecommons.org/licenses/by-nc/4.0/ )
Abstract

Objective: To explore the impact of standardized treatment on perinatal outcomes in pregnant women with hypothyroidism, and to clarify the correlation between the two to provide a reference for clinical diagnosis and treatment. Methods: 160 pregnant women with hypothyroidism who were admitted to our hospital from January 2021 to December 2025 were selected and divided into a standardized treatment group and a conventional treatment group, with 80 pregnant women in each group, using the random number table method. The conventional treatment group adopted the traditional hypothyroidism treatment plan, and the standardized treatment group implemented standardized treatment intervention. After treatment, the two groups of pregnant women were compared on thyroid function indicators, occurrence of adverse perinatal outcomes, and neonatal health indicators. Results: After treatment, the level of thyroid-stimulating hormone in the standardized treatment group was lower than that of the conventional treatment group, and the levels of free triiodothyronine and free thyroxine were higher than those of the conventional treatment group (P < 0.05). The overall incidence of adverse perinatal outcomes in the standardized treatment group was lower than that of the conventional treatment group, and the newborn weight and Apgar score were higher than those of the conventional treatment group (P < 0.05). Conclusion: Standardized treatment for pregnant women with hypothyroidism can effectively improve thyroid function, reduce the risk of adverse perinatal outcomes and improve newborn health. The two are closely related and have clinical promotion value.

Keywords
Pregnancy complicated by hypothyroidism
Standardized treatment
Perinatal outcomes
Thyroid function
Neonatal health
References

[1] Ji SS, Li HW, Pan YS, et al., 2025, Analysis of the Correlation Between Mid-pregnancy Thyroid Function and Maternal and Infant Outcomes in Patients with Gestational Diabetes. Chinese Maternal and Child Health Care, 40(22): 4075–4079.

[2] He SN, Huang ZY, Wang L, 2025, Correlation Between Insulin-like Growth Factor 1 Expression Level and Pregnancy Outcomes in Patients with Subclinical Hypothyroidism During Pregnancy. Chinese Maternal and Child Health Care, 40(22): 4092–4096.

[3] Yu BB, Wu P, Zhou TT, et al., 2026, Analysis of the Clinical Value of Early Pregnancy Thyroid Function Indicators on the Risk of Gestational Diabetes in Pregnant Women. Anhui Medicine, (01): 92–95.

[4] Li LF, Zhang JQ, Yang JH, et al., 2025, Detection of Free Tetraiodothyronine in Cerebrospinal Fluid to Predict Autistic-like Behavior in Offspring Rats Induced by Hypothyroidism During Pregnancy. Journal of Sun Yat-sen University (Medical Science Edition), 46(06): 1029–1040.

[5] Sun WJ, Hou PF, 2025, Establishment and Clinical Significance of Reference Intervals for Thyroid Function Indicators in Healthy Pregnant Women in Lianshui, Huai’an, Jiangsu. Maternal and Child Health Guide, 4(22): 94–97.

[6] Chen Q, Hong PJ, Chen J, et al., 2025, Analysis of Nomogram Prediction Model Constructed by Ultrasound Combined with Serum Hormones and Thyroid Peroxidase Antibodies in Pregnant Women with Threatened Abortion. Chinese Maternal and Child Health Care, 40(23): 4426–4430.

[7] Ma LY, Li QM, Fan LJ, 2025, Relationship Between Serum Fructosamine and PCSK9 Levels, Thyroid Function and Pregnancy Outcomes in Patients with Subclinical Hypothyroidism During Pregnancy. Infection, Inflammation, Repair, 26(05): 380–385.

[8] Zhang F, Cui CQ, Zhang TR, et al., 2025, Association Between Maternal Thyroid Hormone Levels in Early Pregnancy and Gestational Diabetes: A Nested Case-control Study. Chinese Journal of Disease Control, 29(11): 1359–1364.

 

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