Volume 11,Issue 1
Clinical Observation on Treatment of Diabetic Nephropathy with Qihuang Gushen Mixture
Objective: To analyze the effect of Qihuang Gushen Mixture in the treatment of diabetic nephropathy. Methods: From June 2024 to May 2025, 60 patients with diabetic nephropathy were selected for data analysis in the hospital. All patients were divided into two groups using computer random allocation, with 30 patients in each group. The control group was treated with basic Western medicine treatment, while the experimental group was treated with Qihuang Gushen mixture + basic Western medicine treatment. Different treatment effects were observed, and the application value was comparatively analyzed. Results: After treatment, the experimental group was better than the control group in terms of clinical efficacy, renal function indicators, and TCM syndrome improvement, and blood sugar control was more obvious (P<0.05). Conclusion: The treatment of diabetic nephropathy with Qihuang Gushen Mixture can significantly improve the clinical efficacy. It can further improve clinical symptoms on the basis of conventional Western medicine treatment, promote the recovery of renal function, improve the scores of TCM sequelae, and is more conducive to the recovery of the disease. It is worthy of reference.
[1] Yuan Y, Lu JF, Zhao J, et al., 2023, Research on the Clinical Efficacy of Qihuang Jiangtang Hushen Recipe in the Treatment of Diabetic Nephropathy and Its Delaying Effect on Renal Function Damage. Chinese Journal of Traditional Chinese Medicine, 41(1): 35–38.
[2] Han JR, Wang XY, Zhu Q, et al., 2025, Qihuang Gushen Tongluo Recipe Regulates Lipid Metabolism and Autophagy to Protect Podocytes in the Treatment of Diabetic Nephropathy. World Traditional Chinese Medicine, 20(11): 1862–1873.
[3] Guan YR, Wang Y, Liu X, et al., 2025, Overview of Research on the Regulatory Effects of Traditional Chinese Medicine on Signaling Pathways in Diabetic Nephropathy. China Traditional Chinese Medicine Science and Technology, 32(3): 574–578.
[4] Chen JH, 2025, Effect of Qihuang Gushen Tongluo Recipe on the Degree of Renal Damage and Oxidative Stress Indicators in Patients with Diabetic Nephropathy. Inner Mongolia Traditional Chinese Medicine, 44(2): 12–14.
[5] Chen JH, Yang SJ, Xu T, et al., 2023, Research Progress on the Effects of Traditional Chinese Medicine on the Nrf2/HO-1 Signaling Pathway in Diabetic Nephropathy. Modern Hospital, 23(4): 652–656.
[6] Li J, Zhao W, Meng XX, et al., 2023, Research on Modified Qihuang Drink Delaying Diabetic Nephropathy by Reducing Mitochondrial Damage. Journal of Liaoning University of Traditional Chinese Medicine, 25(4): 17–21 + 221.
[7] Li XB, Pang XX, Peng ZN, et al., 2024, Research on Qihuang Gushen Tongluo Prescription in the Treatment of Diabetic Nephropathy Based on Bioinformatics and Animal Experiments. World Traditional Chinese Medicine, 19(5): 615–622.
[8] Wu LY, Mao KF, Xie DD, et al., 2024, Research on the PTEN/PI3K/Akt/mTOR Pathway Mechanism of Modified Qihuang Decoction in Improving Diabetic Nephropathy. Shenzhen Journal of Integrated Traditional Chinese and Western Medicine, 34(7): 4–8 + 137–138.