ARTICLE
26 January 2026

Research Progress on Traditional Chinese Medicine and Extracts for Treating Laryngeal Cancer

Qimeng Zhang1 Yan Liu1 Ziyu Wang1 Yanwei Sun1 Wanyi Zhang1
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1 Hainan Normal University, Haikou 571127, Hainan, China
APM 2026 , 11(1), 165–170; https://doi.org/10.18063/APM.v11i1.1236
© 2026 by the Author. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Abstract

Laryngeal cancer is one of the common malignant tumors of the respiratory tract, most of which occur in the hypopharynx, among which the piriform fossa is the most common. Patients with subglottic laryngeal cancer lose the best treatment time because there are no obvious symptoms, while surgery is still the main treatment for early-stage tumors, and chemotherapy and immunotherapy are adjuvant in the middle and advanced stages. Among them, polysaccharides of traditional Chinese medicine have a significant effect on inhibiting tumors, which has the characteristics of multi-perspective and multi-mechanism synergistic effect, which can avoid drug resistance, and is a new field of natural medicine with great research value and development potential. Traditional Chinese medicine and its extracts mainly treat laryngeal cancer by inhibiting cell cycle and apoptosis, intervening in the metabolism of laryngeal cancer cells, affecting the microenvironment and metastasis of laryngeal cancer cells, and inhibiting the angiogenesis and metastasis of laryngeal cancer cells. This article provides a brief overview of the basic research on the treatment of laryngeal cancer with traditional Chinese medicine and extracts in recent years.

Keywords
Laryngeal cancer
Traditional Chinese medicine
Cellular metabolism
Tumor microenvironment
Drug resistance
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