Volume 11,Issue 2
Application and Feasibility Study of High-Pressure CO₂ Sterilization Technology in Chinese Medicinal Materials Sterilization
Aiming at the risks of excessive microorganisms and irradiation sterilization residues in the direct use of raw powder of Chinese medicinal materials, this paper took the production line of a Chinese patent medicine enterprise as the engineering research object to study the engineering application of high-pressure CO₂ sterilization technology. With the designed sterilization conditions of pressure 30–60 MPa and temperature 35℃–65℃, the raw powder sterilization of medicinal materials with different medicinal parts was completed, and a technical parameter system for industrial application was established. During the project implementation, key technical problems, such as equipment pressure-bearing design, process energy consumption control and multi-round sterilization capacity improvement, were solved. The sterilization effect meets the pharmacopoeia standards, realizing the industrial application goal, and providing a green and safe technical alternative for the sterilization of raw powder of Chinese medicinal materials.
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