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Volume 10,Issue 4

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26 December 2025

Analysis of the Antidota Targets and Pharmacodynamic Material Basis of Pueraria Lobata and Ziziphi Spinosae Compound Formula Based on Metabolomics

Weishuang Tong*
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1 Pingdingshan University, Pingdingshan 467000, Henan, China
JMDS 2025 , 10(4), 164–170; https://doi.org/10.18063/JMDS.v10i4.1203
© 2025 by the Author. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution -Noncommercial 4.0 International License (CC BY-NC 4.0) ( https://creativecommons.org/licenses/by-nc/4.0/ )
Abstract

This study innovatively applies metabolomics technology to deeply analyze the target points and pharmacological substance basis of Ge Gen Zhi Ju compound for sobering up. Through advanced data analysis methods, clarify its key mechanism of action in the process of sobering up, and provide theoretical support for the further development and application of Pueraria lobata and Fructus Aurantii formula.

Keywords
Metabolomics
Compound of Pueraria lobata and Fructus Aurantii
Target of sobering up effect
Pharmacological substance basis
Funding
Supported by Key Scientific and Technological Research Project for Colleges and Universities (Project No.: 23A550020).
References

[1] Che MY, Zhou SN, Wang ZY, et al., 2025, Research Progress on the Protective Effect of Kudzu Root on Alcoholic Liver Injury. Agriculture and Technology, 45(23): 28-32.

[2] Li SQ, Li ZH, Li HS, et al., 2025, Research Progress on the Protective Effect of Chinese Herbal Extracts, Active Ingredients and Compounds on Alcoholic Liver Injury. Traditional Chinese Patent Medicines and Simple Preparations, 47(1): 139-147.

[3] Fang YP, Xu JW, Liu S, et al., 2023, Response Surface Optimization of the Compatibility Ratio of Pueraria Root Houttuynia Cordata Extract for Sobering Up. Journal of Huanggang Normal University, 43(6): 57-62.

[4] Gong P, Wang XJ, Chen XF, et al., 2021, Research on the Preparation Process and Sobering Effect of Compound Blueberry Sobering Tablets. Journal of Shaanxi University of Science and Technology, 39(4): 56-60.

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