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Volume 11,Issue 1

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16 March 2026

Observation of the Effect of Irbesartan + Metoprolol in the Treatment of Hypertension and Analysis of its Impact on effectiveness

Yaxuan Ren*
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1 Jiangning District Second People’s Hospital, Nanjing 210000, Jiangsu, China
JMDS 2026 , 11(1), 36–41; https://doi.org/10.18063/JMDS.v11i1.1350
© 2026 by the Author. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution -Noncommercial 4.0 International License (CC BY-NC 4.0) ( https://creativecommons.org/licenses/by-nc/4.0/ )
Abstract

Objective: To analyze the clinical effectiveness of irbesartan combined with metoprolol in the treatment of hypertension and its impact on the effectiveness. Methods: 76 patients with hypertension admitted to our hospital from December 2023 to December 2024 were selected as the research subjects and divided into two groups using the random number table method. Thirty-eight patients in the experimental group were treated with irbesartan combined with metoprolol, and 38 patients in the conventional group were treated with irbesartan alone. The treatment effectiveness, incidence of adverse reactions, and blood pressure variability indicators before and after treatment were compared between the two groups. Results: The treatment effectiveness of the experimental group was higher than that of the conventional group (P < 0.05); the incidence of adverse reactions between the two groups was not significantly different (P > 0.05); the blood pressure variability index of the experimental group after intervention was better than that of the conventional group (P < 0.05). Conclusion: Irbesartan combined with metoprolol in the treatment of hypertension can improve the therapeutic efficiency, optimize blood pressure variability, and has good safety.

Keywords
Irbesartan
Metoprolol
Hypertension
Therapeutic effect
Blood pressure variability
References

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[8] Shao YX, Sun ZW, Gan XY, et al., 2022, Effects of Combined Treatment with Irbesartan, Hydrochlorothiazide and Metoprolol on Blood Pressure Variability and Cardiorenal Function in Elderly Patients with Hypertension. Chinese Journal of Hospital Pharmacy, 42(24): 2650–2654.

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