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Volume 11,Issue 1

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16 March 2026

Isolation, Identification, and Mechanistic Analysis of Antifungal Secondary Metabolites from Endophytic Fungi in Tropical Medicinal Plants

Decai Dai*
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1 Hainan Vocational University of Science and Technology, Haikou 571126, Hainan, China
JMDS 2026 , 11(1), 190–194; https://doi.org/10.18063/JMDS.v11i1.1372
© 2026 by the Author. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution -Noncommercial 4.0 International License (CC BY-NC 4.0) ( https://creativecommons.org/licenses/by-nc/4.0/ )
Abstract

The symbiotic system between tropical medicinal plants and endophytic fungi harbors a wealth of bioactive secondary metabolites. This project aims to provide potential resources for the development of novel antimicrobial drugs. Building upon previous research, the project will systematically isolate and identify secondary metabolites from endophytic fungi in tropical medicinal plants. By integrating relevant domestic and international research findings, the project seeks to clarify the core technical principles and development directions, thereby offering theoretical support and technical references for the rational utilization of endophytic fungal resources in tropical medicinal plants and the discovery of new antimicrobial active substances in China.

Keywords
tropical medicinal plants
endophytic fungi
antibacterial secondary metabolites
isolation and identification
Funding
Project Category: 2025 University-level Key Research Project of Hainan Vocational University of Science and Technology Project Title: Study on Antibacterial Secondary Metabolites of Endophytic Fungi from Tropical Medicinal Plants and Their Mechanisms of Action Project No.: HKKY2025-ZD-05
References

[1] Zhou SH, Wu ZH, Liao JM, et al., 2020, Isolation and Identification of Cultivable Bacteria from Coral Reef Area of Xieyang Island and Their ECP Antibacterial Activity. Genomics and Applied Biology, 39(02): 644-651.
[2] Sun JL, Wang JL, Wang LY, et al., 2008, Isolation, Extraction, and Structural Identification of Antimicrobial Active Substances from Secondary Metabolites of Streptomyces SPRI10304. Chemical and Biological Engineering, (01): 43-45+51.
[3] Chen HB, Zhang M, Yang CP, et al., 2007, Study on the Fungicidal Activity of A2C Strain and Preliminary Identification of the Strain. Jiangsu Agricultural Science, (02): 72-74+157.

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