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Volume 10,Issue 4

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20 December 2025

To Explore the Clinical Effect of Self-made Shugan Jianzhong Decoction in the Treatment of Helicobacter Pylori (Hp)-positive Chronic Atrophic Gastritis (CAG) with Liver and Stomach Stagnation Heat Type

Xiaorong Zhao1
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1 Nanjing Zhetang Central Health Center, Nanjing 211200, Jiangsu, China
APM 2025 , 10(4), 282–288; https://doi.org/10.18063/APM.v10i4.1060
© 2025 by the Author. Licensee Whioce Publishing, Singapore. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/ )
Abstract

Objective: To analyze the effect of self-prepared Shugan Jianzhong Decoction in the treatment of Helicobacter pylori (Hp)-positive chronic atrophic gastritis (CAG) caused by liver and stomach stagnation heat. Methods: 90 Hp-positive CAG patients with liver and stomach stagnation and heat in the hospital from 2023.3 to 2024.3 were divided into control group and observation group by random number table method. They were treated with quadruple therapy and quadruple therapy plus self-made Shugan Jianzhong Decoction respectively to compare the effects. Results: Through different treatment plans, the treatment effectiveness and Hp clearance rate of the observation group were higher than those of the control group; the TCM syndrome scores of the observation group were lower than those of the control group; the levels of gastric function indicators were higher than those of the control group; the levels of inflammatory factors were lower than those of the control group (p < 0.05); the incidence of adverse reactions was similar between the two groups (p > 0.05). Conclusion: The self-prepared Shugan Jianzhong Decoction is effective in treating Hp-positive CAG diseases. It has significant advantages in clearing Hp, promoting symptoms and improving gastric function. It is safe and reliable when used in combination with western medicine and is worthy of promotion.

Keywords
Liver and stomach stagnation heat
Helicobacter pylori
Chronic atrophic gastritis
Shugan Jianzhong Decoction
References

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